Cyclohexanone monooxygenase (CHMO)
Description:
De cyclohexanone monooxygenase
ES-CHMO (Cyclohexanone monooxygenase): a Baeyer Villiger monooxygenas (BVMO) cum cyclohexanone ut subiectae, cyclohexanonem oxidizare potest ad cyclohexanolum utens oxygeni.
Est genus flavinum enzyme dependens.Flavin oxidized ad flavinum redigitur per cyclum reducendi coenzyme II (NADPH) ad oxidationem proximam.Ergo necesse est cofactor NADPH in cyclo flavino.Solum 1 genus productum enzyme CHMO (Number sicut ES-CHMO101) a SyncoZymes evolvit, quod ad cyclohexanonem oxidizandum adhiberi potest.
Genus reactionem catalytic:
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| Enzymes | Product Code | Specification |
| Ornamentum protegendo (SynKit) | ES-CHMO-101 | a paro of 1 Ketoreductases, 1 mg sulum 1 items * 1mg / item |
Substantiae Substantiae High.
Chiral selectivity strong.
Maximum conversionem.
★ Minus per-producta.
★ Mitis reactionis condiciones.
★ Environmentally amica.
➢ Communiter, ratio reactionis includit subiectum, solutionem quiddam, enzyme, coenzyme et coenzyme systematis regenerationis (eg glucose et dehydrogenasis glucose).
➢ CHMO novissime in systema reactionis addi debet, post pH et temperatus condicionem reactionem adaequatum.
Exemplum 1 (Synthesis cyclohexanol e cyclohexanol)(1):
Custodi 2 annos infra -20℃.
Numquam attingunt extremas condiciones ut: caliditas, alta/humilis pH et altae concentrationes organicae solvendo.
1. Friso, Marco, Appl Microbiol Biotechnol, 2017, 101(20): 7557-7565
