SyncoZymes

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  • Ketoreductase (KRED)

    Ketoreductase (KRED)

    About Ketoreductase

    Enzymes: catalystae macromoleculares biologicae, maxime enzymes sunt servo.

    Ketoreductase: Etiam "Carbonyl reductase" dicuntur, sunt enzymes quae reactionem convertibilem redox inter aldehydes / ketones et alcoholos catalyzunt, ac coenzyma ut H transmittentes ut NADH vel NADPH egent.Tria genera praecipua KRED: Brevis catena Dehydrogenas / Reductases (SDRs), Medium-catenae Dehydrogenas / Reductases (MDRs), et Aldo-KetoReductases (AKRs).Munera catalytica tria sunt similia, sed structura et proprietas prorsus diversae sunt.

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  • Transaminase (ATA)

    Transaminase (ATA)

    De transaminase

    ATA ex SyncoZymes: Sunt 66 species productorum enzymorum ATA (Number sicut ES-ATA-101~ES-ATA-166) evolvit SyncoZymes.SZ-ATA utile est instrumentum ad catalysin regio- et stereosellectivam synthesin chiralorum aminum, amino acida eorumque derivata ex variis ketoacidarum aliphaticorum et aromaticorum, aldehydes, ketones et ketoses.

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  • Nitrilase (NIT)

    Nitrilase (NIT)

    De Nitrilase

    ES-NITs: Circulum cyanidum directe ad catervam carboxylicam convertendam, ad praeparandum acidum carboxylicum, quod late in medicina, tutela environmentali, industria chemico, cibo additivo, textili, productione agriculturae aliisque agris adhibetur.
    Sunt 40 genera productorum nitrilasiorum (NIT) (Number sicut ES-NIT-101~ES-NIT-140) per SyncoZymes evoluta.ES-NIT instrumentum utile est ad synthesim acida carboxylica chiralis catalysis per regio- stereoselectivam hydrolysim amplis nitrilibus aliphaticis et aromaticis.

    Genus reactionem catalytic:

    Nitrilase NIT2

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  • Nitrile hydratase (NHT)

    Nitrile hydratase (NHT)

    Circa ES-NHTs

    ES-NHTs: genus metalloenzyme, quod nitriles selective hydrae in primaria amids respondente.Late adhibentur non solum ad summam amino acidorum, amidum, acida carboxylica eorumque derivata, sed etiam ad medicamenta chiralia conficienda.Sunt 24 genera hydratasium nitrilium a SyncoZymes evoluta (Number sicut ES-NHT-101~ES-NHT-124).
    Genus reactionem catalytic:

    Nitrile hydratase NHT2

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  • Amidase (AMD)

    Amidase (AMD)

    AMD e SyncoZymes: Sunt 19 genera productorum AMD enzymorum (Number sicut ES-AMD-101~ES-AMD-119) per SyncoZymes explicatus.SZ-AMD instrumentum utile est ad catalysin regio- et stereoselectivam synthesim acidarum carboxylicarum chiralium earumque derivatorum e variis amids aliphaticis et aromaticis.

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  • Ene reductase (ERED)

    Ene reductase (ERED)

    About ene reductase

    ES-EREDs: Ad familiam veterum enzymorum flaviorum pertinentium quae selective minuunt C=C in α, β - compositorum cum electronico-convivio insatiabili.Late adhibentur in studio derivatorum amino acidorum, substantiarum bioactivarum, intermedia pharmaceutica, aromata et cuneos chirale.

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  • Oxynitrilases (HNL)

    Oxynitrilases (HNL)

    De oxynitrilases

    ES-HNLs: Genus enzyme quod enantioselective catalyzae additionem HCN ad aldehydes (ketones) obtinendum R vel S genus alcoholi cyanidum, quod facile in multas species medicamentorum vel medicamentorum mediarum per methodum chemicam converti potest.
    Genera oxynitrilasi productorum 29 (Number sicut ES-HNL-101~ES-HNL-129) a SyncoZymes evolvit.SZ-HNL instrumentum utile est ad synthesin regio- et stereo- selectivam (R) cyanohydrinorum seu (S) cyanohydrinorum ex variis aromaticis, aliphaticis et heterocyclicis aldehydis vel etiam ketonibus.
    Genus reactionem catalytic:

    Oxynitrilases HNL2

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  • Nitro reductase (NTR)

    Nitro reductase (NTR)

    De nitro reductase

    ES-NTRs: Sunt flavoenzymae quae NAD (P)H-dependentes reductionem gregum nitroaromaticorum et nitroheterocyclicarum compositorum in hydroxylamino et/vel amino derivationes catalysinant.Late adhibentur in synthesi organica hydroxylamini aromatici et amini aromatici, therapiae tumoris, detectionis biologicae et deiectionis pollutentium environmental.Sunt 12 genera productorum Nitro (NTR) productorum (Number sicut ES-NTR-101~ES-NTR-112) a SyncoZymes explicatus.

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  • Aldolase (DERA)

    Aldolase (DERA)

    ES-DERAs: Potest efficaciter catalydere stereoselectivam additionem donatoris ketones receptori aldehydi.Praeterea, reactionem in aquea solutione neutrorum pH sine specialibus remediis tutelaribus exerceri potest.Ad classem I aldolasium pertinent, quae in processu catalytico basim Shiff format.Subiectum covalenter coniungitur cum amino coetus situs activi ad initium ruptionis et formationis vinculi.Discrimen inter DERAs et alias aldolases est quod subiectae catalyse sunt aldehydes et continuam aldehydes condensationem subire possunt.

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  • Cytochrome P450 monooxygenase (CYP)

    Cytochrome P450 monooxygenase (CYP)

    De CYP

    ES-CYPs: Classis redox enzymorum cum mercaptan-heme sicut centrum activum ad translationem oxygenii catalysin.Eae terminales oxygenases ac necessitates heme ad activate oxygeni.

    Cytochrome P450 monooxygenase oxidationis, epoxidationis et hydroxylationis alkyl, hydroxylationis et oxidationis ammoniaci, oxidationis sulphuris, dealkylationis (oxygeni, sulphuris, ammoniaci), siccitatis oxidativae, deaminationis et dehalogenationis.
    Genera cytochromi P450 monooxygenas sunt octo (Number sicut ES-CYP-101~ES-CYP-108) enucleata per SyncoZymes.

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    E-Mail:lchen@syncozymes.com

  • Sin oxidase (AOX)

    Sin oxidase (AOX)

    De alcohole oxidase

    ES-AOXs: Hae enzymes oxidationes pingues alcoholorum vel aryl-alcoholarum ad aldehydes formandas valent.Utuntur oxygeni moleculares, sed cofactorem exterius additum non requirit, et hydrogenium peroxide productum est.

    Triginta genera oxydatum alcoholi (Number sicut ES-AOX-101~ES-AOX-106) per SyncoZymes evolvit.ES-AOX101 et ES-AOX102 potius alcoholi aliphatici subiectae, ES-AOX103~ ES-AOX105, potius alcoholi aromatici subiectum, et ES-AOX106 oxidasis cholesteroli est.SZ-AOX utile est instrumentum ad oxidationes catalysndas alcoholorum pingues vel aryl-alcoholas ad aldehydes producendas.

    Genus reactionem catalytic:

    AOX'

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    E-Mail:lchen@syncozymes.com

  • Acidum dehydrogenase D-Amino (D-AADH)

    Acidum dehydrogenase D-Amino (D-AADH)

    Circa D-Amino acidum dehydrogenase

    ES-D-AADH (Acidi dehydrogenas D-Amino): enzymum quod acidum 2-keto in acidum D-amino respondente reducere potest.Reactio eget NADP (H) et donatoris ammoniaci inorganici (ut ammonia vel ammonium ion).D-amino acidorum dehydrogenas genera sunt 17 (Number ut ES-DAADH-CI~ES-DAADH-117) a SyncoZymes evolvit.

    Genus reactionem catalytic:

    D-Amino acidum dehydrogenase2

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    E-Mail:lchen@syncozymes.com

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